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Run the Ordinal SuStaIn algorithm (OSA) or load results from presaved .rds file if available

Usage

run_and_save_OSA(
  dataset_name,
  output_folder,
  verbose = TRUE,
  N_S_max,
  rerun = FALSE,
  rda_filename = "data.RData",
  ...
)

Arguments

dataset_name

for naming pickle files

output_folder

where to save pickle files, etc.

verbose

logical() indicating whether to print debugging information

N_S_max

maximum number of subtypes, should be 1 or more

rerun

whether to force a rerun of the python code

rda_filename

name of rda file containing environment used to run analyses

...

Arguments passed on to run_OSA

prob_score

array probability of each score for all subjects across all biomarkers

  • dim = number of subjects x number of biomarkers x number of scores

score_vals

a matrix specifying the scores for each biomarker

  • dim: number of biomarkers x number of scores

SuStaInLabels

the names of the biomarkers as a list of strings

N_startpoints

number of startpoints to use in maximum likelihood step of SuStaIn, typically 25

N_iterations_MCMC

number of MCMC iterations, typically 1e5 or 1e6 but can be lower for debugging

use_parallel_startpoints

boolean for whether or not to parallelize the maximum likelihood loop

seed

random number seed for python code

plot

logical() indicating whether to construct PVD plots via python subroutines

N_CV_folds

number of cross-validation folds to create

patient_data

patient biomarker data

CV_fold_nums

which CV folds to run (for parallel processing)

keep_data

logical() indicating whether to include the ata in the return object

fig_size

python figure size, in inches (width, height)

prob_correct

the probability of correctly classifying the underlying biomarker level: p(obs = true)

biomarker_levels

a list containing the levels for each biomarker

Value

a list()